P38 MAPK/NF-kB信号通路在支气管哮喘发病机制中的作用研究-国际临床研究杂志-CSCIED科技核心评价数据库-手机版

P38 MAPK/NF-kB信号通路在支气管哮喘发病机制中的作用研究

The role of P38 MAPK/NF KB signal pathway in the pathogenesis of bronchial asthma

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DOI	10.12208/j.ijcr.20230279
刊名	国际临床研究杂志 International Journal of Clinical Research
年，卷(期)	2023, 7(7)
作者	张予暄¹,雷勋明²*,
作者单位	1 成都医学院附属妇女儿童医院儿童健康中心四川成都 ; 2 四川省妇幼保健院儿童健康中心四川成都 ;
摘要	神经信号转导通路可以通过不同的方式、途径等对呼吸道的相关细胞组织起到一定的影响作用，研究发现其参与了支气管哮喘的气道炎症和气道重塑，本文综述了p38 MAPK/NF-kB信号通路在支气管哮喘发病机制中的研究进展，进一步了解神经信号转导通路有助于探索哮喘的发生机制，为哮喘的临床治疗提供更精确更新颖的靶点，对未来研究新药、提高相关疾病临床疗效均有重要意义。
Abstract	The neural signal transduction pathway can play a certain role in influencing the relevant cell tissues of the respiratory tract through different ways and pathways, thus inducing the occurrence and development of bronchial asthma. This article reviews the research progress of p38 MAPK/NF kB signal pathway in the pathogenesis of bronchial asthma, and further understands the neural signal transduction pathway is helpful to explore the pathogenesis of asthma, to provide more accurate targets for the clinical treatment of asthma, which is of great significance for the future research of new drugs and the improvement of clinical efficacy of related diseases.
关键词	支气管哮喘；发病机制；p38 MAPK信号通路；NF-kB信号通路
KeyWord	Bronchial asthma; Pathogenesis; P38 MAPK signal pathway; NF kB signal path
基金项目
页码	18-22

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引用本文

张予暄,雷勋明*. P38 MAPK/NF-kB信号通路在支气管哮喘发病机制中的作用研究 [J]. 国际临床研究杂志. 2023; 7; (7). 18 - 22.

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