rankl/opG介导的中耳胆脂瘤骨质破坏的研究进展

Progress in rankl / opG mediated bone destruction in middle ear choleslipoma

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DOI 10.12208/j.ijcr.20230331
刊名
International Journal of Clinical Research
年,卷(期) 2023, 7(10)
作者
作者单位

佳木斯大学附属第一医院 黑龙江佳木斯 ;

摘要
近年来,rankl已经被证实具有重要的作用,其作为肿瘤坏死的关键因素,可以促进胆脂瘤的形成,从而导致耳部的损伤,影响耳部的健康。胆脂瘤的出现,给耳部健康带来了极大的威胁,它的出现,将严重影响耳部的生理机制,且还会导致耳聋。采用多种措施来促进骨骼的正常生长,可以有效减缓中耳胆脂瘤的恶变。opG可以有效地抑制rankl的形成,减少胆脂瘤对骨组织的损伤。为此,本文对rankl/opG介导的中耳胆脂瘤骨质破坏进行简要阐述以及分析研究,本次实验主要通过对近几年的研究以及文献报告进行整理,为中耳胆脂瘤骨质破坏的治疗方法提供新思路。
Abstract
In recent years, rankl has been proved to play an important role. As a key factor of tumor necrosis, it can promote the formation of cholesteatoma, thus leading to ear damage and affecting the health of the ear. The appearance of cholesteatoma brings a great threat to the ear health, which will seriously affect the physiological mechanism of the ear, and will also lead to deafness. Various measures to promote the normal growth of bones can effectively slow down the malignant changes of middle ear cholesteatoma. The opG can effectively inhibit rankl formation and reduce the damage to bone tissue by cholesteatoma. To this end, this paper briefly expounds and analyzes the bone destruction mediated by rankl / opG. This experiment mainly provides new ideas for the treatment of bone destruction of middle ear cholesteatoma through the collation of research and literature reports in recent years.
关键词
rankl;中耳胆脂瘤;骨质破坏;研究进展
KeyWord
Rankl; Middle ear cholesteatoma; Bone destruction; Research progress
基金项目
页码 36-39
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徐停伟,周旭峰*. rankl/opG介导的中耳胆脂瘤骨质破坏的研究进展 [J]. 国际临床研究杂志. 2023; 7; (10). 36 - 39.

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