International Journal of Clinical Research

Objective To investigate the factors affecting the clinical pregnancy rate of artificial insemination (AIH). Methods A total of 178 cycles of AIH in the Reproductive Medicine Center of Hunan Peoples Hospital from 2017 to 2022 were retrospectively analyzed. The effects of infertility type, infertility cause, treatment, follicle size on trigger day, E2 level on trigger day, total number of forward motile sperm (PR) after treatment and ovulation on clinical pregnancy rate were analyzed. Results 25 cycles of clinical pregnancy were obtained from 178 cycles of artificial insemination, and the clinical pregnancy rate was 14.04%. Pregnancy and pregnancy group between the fixed number of year of the couples age, infertility, trigger, lining thickness and former PR has no obvious difference between the total number of (P ˃ 0.05).The clinical pregnancy rate in the primary infertility group was higher than that in the secondary infertility group, the clinical pregnancy rate in letrozole ovulation induction was slightly higher than clomiphene ovulation induction and natural cycle ovulation induction. The clinical pregnancy rate in trigger day follicles < 18mm did not decrease, but the clinical pregnancy rate decreased with the decrease of E2 level on trigger day. The clinical pregnancy rate didn,t decrease significantly with the total PR < 10 million after treatment. Pregnancy rate slightly increased, but the difference is compared between these groups had no statistical significance (P ˃ 0.05),clinical pregnancy rate of the male factor infertility patients of AIH is highest, the difference was statistically significant (P < 0.05). Conclusion Male factor infertility is the best indication for male sperm artificial insemination. For patients with PR < 10 million after treatment, male sperm artificial insemination can also be attempted. When trigger day follicle < 18mm, the E2 level can be combined to decide whether to abandon AIH cycle.

Infertility; Artificial Insemination; Correlation factor