JPBS

Objective: To explore the effect of comorbid obsessive-compulsive personality disorder (OCPD) on response inhibition functions in patients with obsessive-compulsive disorder (OCD). Methods: Forty-five obsessive-compulsive patients with obsessive-compulsive personality disorder, 42 obsessive-compulsive patients without obsessive-compulsive personality disorder and 54 healthy volunteers were selected for the stop-signal task. Results: Obsessive-compulsive patients with obsessive-compulsive personality disorder had a higher score of depression and anxiety and more severe obsessive-compulsive symptoms than that of obsessive-compulsive patients without obsessive-compulsive personality disorder. The two groups of obsessive-compulsive patients of had a greater stop-signal reaction time (SSRT) during the inhibition process than the healthy volunteers of the control group. However, no significant difference was found between the two groups of obsessive-compulsive patients. Conclusion: The findings show that the comorbid obsessive-compulsive personality disorder has no effect on response inhibition function of obsessive-compulsive patients.

Obsessive-compulsive disorder; Obsessive-compulsive personality disorder; Response inhibition; Comorbidity