International Journal of Clinical Research

The patient, female, 19 years old. Dense brownish brown spotted papules Between the breast, chest and back, slightly itching for 4 years. The patient has no obvious inducement. There are large brown red papules with rice grains in Between the breast and front chest, which are occasionally itchy. The rear rash gradually increases, increases and involves the inner side of both breasts and spreads to the shoulder, back and waist, forming a dense reticular appearance. Direct microscopic examination of back dander: a small amount of round spores can be seen. Histopathology showed mild keratinization of epidermis, thinning of granular layer, hypertrophy of spinous layer, mild edema of dermis, and nonspecific inflammatory cell infiltration around blood vessels. Diagnosis:Confluent and reticulated papillomatosis. After oral administration of itraconazole and minocycline, combined with external washing of traditional Chinese medicine and external application of retinoic acid cream, satisfactory results were obtained. The reticular pigmentation of shoulder, back and waist subsided after 2 times of photon treatment, and there was no recurrence after 1 year of follow-up. Its treatment method is worthy of reference.

Cutaneous Papillomatosis; Brown Papules; Fused Into A Network