International Journal of Clinical Research

Objective To explore and compare the efficacy of glycosylated hemoglobin and serum C-peptide detection in the diagnosis of diabetes. Methods: A total of 62 suspected diabetic patients and 58 healthy people who were admitted to our hospital from March 2020 to February 2021 were selected as the analysis objects. Fasting venous blood was collected from all personnel, and serum C-peptide, glycosylated hemoglobin, fasting blood glucose and 2h postprandial blood glucose were detected. Results: The serum C-peptide level of diabetic patients was (0.80±0.28) ug/L lower than that of healthy people, the glycated hemoglobin (9.08±1.52)%, fasting blood glucose (8.82±1.61) mmol/L and 2h postprandial blood glucose (12.62±2.22) ) mmol/L was higher than that of healthy people, the difference was P<0.05; A total of 58 of the 62 suspected patients were diagnosed with diabetes. The diagnostic results of serum C-peptide and glycosylated hemoglobin were comparable (P>0.05), and the combined diagnostic sensitivity (93.10%), specificity (75.00%), missed diagnosis rate (6.90%) and misdiagnosis rate (25.00%) were all excellent in a single diagnosis (P<0.05). Conclusion: The combined detection of glycosylated hemoglobin and serum C-peptide is more conducive to reducing the risk of misdiagnosis in the diagnosis of diabetes, and it is worthy of promotion.

Diabetes; Serum C-Peptide; Glycosylated Hemoglobin; Blood Sugar