Psychiatric Genetics, Epigenetics, and Cellular Models in Coming Years-Journal of Psychiatry and Brain Science-CSCIED科技核心评价数据库-手机版

Psychiatric Genetics, Epigenetics, and Cellular Models in Coming Years

Psychiatric Genetics, Epigenetics, and Cellular Models in Coming Years

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DOI	10.20900/jpbs.20190012
刊名	Journal of Psychiatry and Brain Science JPBS
年，卷(期)	2019, 4(4)
作者	Chunyu Liu*,Stephen V. Faraone,Stephen J. Glatt,
作者单位	Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY 13210, USA
Abstract	Psychiatric genetic studies have uncovered hundreds of loci associated with various psychiatric disorders. We take the opportunity to review achievements in the past and provide our view of what is coming in the fields of molecular genetics, epigenetics, and cellular models. We expect that SNP-array and sequencing-based studies of genetic associations will continue to expand, covering more disorders, drug responses, phenotypes, and diverse populations. Epigenetic studies of psychiatric disorders will be another promising field with the growing recognition that environmental factors impact the risk for psychiatric disorders by modulating epigenetic factors. Functional studies of genetic findings will be needed in cellular models to provide important connections between genetic and epigenetic variants and biological phenotypes.
KeyWord	psychiatry; genetics; epigenetics; behavior; population diversity; function study; drug response; cellular phenotype; molecular phenotype; regulatory network
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引用本文

Chunyu Liu*,Stephen V. Faraone,Stephen J. Glatt. Psychiatric Genetics, Epigenetics, and Cellular Models in Coming Years, Journal of Psychiatry and Brain Science. 2019; 4; (4). https://doi.org/10.20900/jpbs.20190012.

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