| 作者单位 |
École de réadaptation, Faculté de médecine et des sciences de la santé, Université de Sherbrooke, J1H 5N4 Québec, Canada ; École de santé publique, Département dadministration de la santé, Université de Montréal, H3N 1X9 Québec, Canada ; McGill University-University of Montreal Research Group on Frailty and Aging (SOLIDAGE), Montreal, H3T 1E2 Québec, Canada ; Research Center on Aging, Sherbrooke, J1H 4C4, Québec, Canada ; Research Center, Centre hospitalier universitaire de Sherbrooke, Sherbrooke, J1H 5H3 Québec, Canada ;
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| Abstract |
Only 4–7% of people aged 65–74 are considered frail. However, this youngest-old subgroup may live for several decades with chronic diseases and reduced quality of life. Therefore, it is essential to identify how life-course factors contribute to the manifestation of individual frailty components in order to design interventions that could prevent or mitigate their adverse effects in community-dwelling youngest-old. This study explored whether lifestyle habits (tobacco/alcohol consumption, sleep quality), geographic location (metropolitan/urban/semi-rural), and type of work increase the risk of exhibiting frailty components at a younger age. Using a cross-sectional design involving 1643 community-dwelling older adults (65+), logistic regression models showed that current but not past smoking was strongly related to low physical activity earlier in life (OR: 3.08; CI: 1.12–8.44). Lifetime number of cigarettes smoked also significantly increased the risk of exhibiting this frailty component in the youngest-old subgroup only. Poor sleep contributed to another frailty component (exhaustion) (OR: 2.52; CI: 1.46–4.37), while moderate alcohol consumption was a protective factor against three frailty components. However, these relationships were not found exclusively in the youngest-old. Living in an urban area was the only factor that contributed significantly less to individual frailty components (slowness) with advancing age, when compared to semi-rural areas. This study expands on previous work by exploring the contribution of life-course factors pertaining to lifestyle, geographic location and type of work to the manifestation of specific frailty components in the youngest-old. Our findings may support the adaptation of public policy programs (e.g., stop smoking program for young older adults) to prevent the early manifestation of frailty.
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