AGMR

The significant impact that some classes of drugs may have on older and frail people is nowadays an emerging issue. In particular, anticholinergics play a central role in this field. The systematic review and meta-analysis conducted by Stewart and colleagues, in accordance with the emerging literature on this topic, clearly demonstrate that an increased anticholinergic burden seems linked with low physical function and poor quality of life. This result underlines the well-established need of medication review, reconciliation, and a deprescribing activity during the clinical assessment of the older person.

anticholinergics; anticholinergic burden; polypharmacy; frailty