The Impact of Sleep on Neurocognition and Functioning in Schizophrenia—Is It Time to Wake-Up?

The Impact of Sleep on Neurocognition and Functioning in Schizophrenia—Is It Time to Wake-Up?

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DOI 10.20900/jpbs.20220001
刊名
JPBS
年,卷(期) 2022, 7(1)
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作者单位

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA ;
Division of Pulmonary, Critical Care and Sleep Medicine, Mount Sinai Integrative Sleep Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA ;

Abstract
People with schizophrenia (SZ) display substantial neurocognitive deficits that have been implicated as major contributors to poor daily functioning and disability. Previous reports have identified a number of predictors of poor neurocognition in SZ including demographics, symptoms, and treatment adherence, as well as body mass index, aerobic fitness, and exercise activity. However, the putative impact of sleep has received relatively limited consideration, despite sleep disturbances, which are pervasive in this population, resulting in symptoms that are strikingly similar to the neurocognitive deficits commonly observed in SZ. Here we argue for the consideration of the impact of sleep on neurocognition in people with SZ and propose recommendations for future research to elucidate the links between sleep parameters, neurocognition and daily functioning.
KeyWord
sleep; neurocognition; schizophrenia; slow wave sleep; spindles; functioning; psychosis
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David Kimhy*,Luz Ospina,Katie Beck-Felts,Ahmad Fakhoury,Anna Mullins,Andrew Varga. The Impact of Sleep on Neurocognition and Functioning in Schizophrenia—Is It Time to Wake-Up?, Journal of Psychiatry and Brain Science. 2022; 7; (1). https://doi.org/10.20900/jpbs.20220001.

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