International Journal of Clinical Research

Objective To investigate variation characteristics of cerebral neurotransmitter on anxiety-depression Patients with somatic symptoms by encephalonuctuograph(EFG)．And to investigate the clinical symptom of patients were studied in the increase of brain fluctuation neurotransmitter function and the decrease. Methods 210 cases with anxiety and depression in Chengdu first Peoples Hospital outpatient and inpatient patients in August 2018 to March 2019 were chosen, in line with the inclusion criteria and exclusion criteria, Participants were assessed by SCL-90 and somatic symptoms in 1-3 days，and the relative value of six kinds of neurotransmitters(GABA，5-HT，DA，Ach，NE，Glu)were measured by Encephalofluctuograph (EFG).Results The positive rate of psychological assessment in 210 patients was 71.5%, which made the positive rate assessed by Encephalofluctuograph (EFG) instrument 100%. The level of neurotransmitters in the brain function increase group was significantly higher than that in the lower group(P<0.05). Compared with the two groups of SCL-90 assessment, the brain function increase group had higher scores in somatic, scary, psychotic component syllables than the decreased group(P<0.05).and the two groups of clinical symptoms compared，the brain function increase group with lower incidence of dizziness, weakness, palpitation, weight loss, and tremor symptoms(P<0.05). Conclusion There were false negatives in the dosage table of patients with anxiety and depression, which showed physical symptoms, while the brain fluctuation map could accurately evaluate the neurotransmitter abnormalities. There were differences in symptom scale and somatic symptom expression between the increase of brain fluctuation transmitter and the decrease of group.

Encephalofluctuograph; Depression And Anxiety; Somatic Symptoms; Neurotransmitter