International Journal of Clinical Research

Objective: To explore the effect of intensive nursing intervention on intestinal graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Methods: a total of 70 patients treated with allogeneic hematopoietic stem cell transplantation in our hospital from January 2019 to February 2022 were selected. Postoperative physical examination showed that they were complicated with intestinal graft-versus-host disease. The envelope method was established and divided into two groups: routine group and experimental group, with 35 people in each group. Routine nursing intervention was given to the routine group and intensive nursing intervention was given to the experimental group. The nursing satisfaction, course of disease and length of hospital stay, and the scores of adverse emotions before and after nursing were compared between the two groups. Results: before the intervention, the scores of bad emotions in the two groups were compared (P > 0.05). After the intervention, the nursing satisfaction of the experimental group was higher than that of the routine group (P < 0.05). The course of disease, length of hospital stay and adverse emotion score in the experimental group were lower than those in the routine group (P < 0.05). Conclusion: the establishment of intensive nursing intervention program for patients with intestinal graft-versus-host disease after allogeneic hematopoietic stem cell transplantation can shorten their rehabilitation leave and improve the evaluation of service quality. It is suggested to popularize it.

Allogeneic Hematopoietic Stem Cell Transplantation; Intestinal Graft Versus Host Disease; Intensive Nursing; Effect