利多卡因致过敏性休克相关的文献分析-国际临床研究杂志-CSCIED科技核心评价数据库-手机版

利多卡因致过敏性休克相关的文献分析

Literature analysis of anaphylactic shock induced by lidocaine

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DOI	10.12208/j.ijcr.20230010
刊名	国际临床研究杂志 International Journal of Clinical Research
年，卷(期)	2023, 7(1)
作者	王铭,吕晓雨,罗雨青,王新军,谢忠珊,潘险峰*,
作者单位	昆明医科大学云南昆明 ; 中国人民解放军联勤保障部队第九二〇医院云南昆明 ;
摘要	常用局麻药据其化学结构可分为酯类和酰胺类。目前，大多数局部麻醉是使用酰胺类进行的。而利多卡因被认为是酰胺局部麻醉剂的原型。其以起效迅速，药效持续时间适中，过敏最少等的优点得以广泛应用。但是，近年来有关利多卡因不良反应（ADR）的报道逐渐增多，使得其受到广泛关注，在对ADR发生因素进行探究的过程中，得出结论对局麻药的真正过敏反应极为罕见，不到所有局麻药ADR的1%。因此，本文将对利多卡因过敏的流行病学、致敏原因、临床表现、评估及相关诊断方法展开如下综述。
Abstract	Commonly used local anesthetics can be divided into esters and amides according to their chemical structures. Currently, most are performed with amide anesthetics. Lidocaine is considered to be the prototype of amide local anesthetics. It has been widely used due to its advantages such as working quickly, moderate duration of drug effect, and least allergies. However, in recent years, reports of adverse reactions(ADR) to lidocaine have gradually increased, which has attracted widespread attention. During the process of investigation, it was found that true allergic reactions to local anesthetics are extremely rare, Less than 1% of all local anaesthetic ADRs. Therefore, the epidemiology, sensitization causes, clinical manifestations, evaluation and related diagnostic methods of lidocaine allergy are reviewed as follows.
关键词	利多卡因；局麻药；不良反应；过敏性休克；超敏反应；诊断方法
KeyWord	Lidocaine; Local Anesthetics; Adverse Reactions; Anaphylactic Shock; Hypersensitivity Reactions; Diagnostic Method
基金项目
页码	33-38

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王铭,吕晓雨,罗雨青,王新军,谢忠珊,潘险峰*. 利多卡因致过敏性休克相关的文献分析 [J]. 国际临床研究杂志. 2023; 7; (1). 33 - 38.

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