International Journal of Medicine and Data

Objective: To To explore the clinical effect of aripiprazole combined with olanzapine in the treatment of female schizophrenia. Methods: 128 female schizophrenics in our hospital from January 2018 to December 2020 were selected and divided into a combined group and a control group according to different treatment schemes, with 64 patients in each group. The combined group was treated with olanzapine+aripiprazole, while the control group was only treated with olanzapine. The therapeutic effects and adverse reactions of the two groups were compared. Results: After treatment, the total effective rate of the combined group was 92.19% higher than that of the control group (71.88%, P<0.05); After treatment, sleepiness, weight gain and menstrual disorder in the combined group were less than those in the control group (P<0.05). Conclusion: Olanzapine plus aripiprazole can further improve the blood glucose and lipid levels, improve clinical efficacy and reduce adverse reactions in female schizophrenia patients.

Schizophrenia; Blood glucose; Aripiprazole; Blood lipid; Olanzapine