International Journal of Medicine and Data

Hepatocellular carcinoma (HCC) is a kind of malignant tumor which is a serious threat to human health. It has a high degree of malignancy, insidious onset and atypical early symptoms. Most patients already belong to the middle or late stage and lose the opportunity of surgery when diagnosed. Although some patients can be treated with surgery, postoperative recurrence and metastasis still seriously affect the survival of patients. Early detection and diagnosis is the key to successful clinical treatment and improved prognosis of patients with liver cancer. If tumor recurrence is inevitable, how to detect early recurrence and metastasis, and take timely intervention, is particularly important. At present, there is a lack of specific examination methods for early screening and prognosis. Liquid biopsy techniques based on circulating tumor DNA(ctDNA) have gained rapid and widespread interest in recent years. Therefore, this paper discusses the application of circulating tumor DNA in the diagnosis and treatment of liver cancer.

hepatocellular carcinoma; circulating tumor DNA