International Medical Research Frontier

Objective To investigate the effect and curative effect of tiotropium bromide inhalation on the pulmonary function of elderly patients with chronic obstructive pulmonary disease in acute exacerbation. Methods Seventy-eight elderly patients with chronic obstructive pulmonary disease in acute exacerbation were selected and randomly divided into control group and observation group, with 39 cases in each. The control group was treated with glucocorticoid; the observation group was treated with tiotropium bromide inhalation. Results There was no difference in lung function and blood gas indexes between the control group and the observation group before treatment (P>0.05). After treatment, the indexes in the observation group were significantly higher than those in the control group (P<0.05). The PCO2 in the observation group was lower than that in the control group (P < 0.05), PAO2 was higher than that of the control group (P < 0.05); compared with the two groups of effective rates, the observation group was better than the control group (P < 0.05). Conclusion The application of tiotropium bromide inhalation in the treatment of elderly COPD patients with acute exacerbation can effectively improve the quality of life of patients, stabilize the pulmonary function and blood gas indicators, avoid complications, reduce patients fear, improve cooperation compliance, and curative effect. good and worthy of wide application.

Chronic obstructive pulmonary disease; Acute exacerbation; Pulmonary function; Blood gas; Glucocorticoid; tiotropium bromide inhalation; Efficacy