动物源性食品中类固醇激素的快速检测方法研究进展

Research progress on rapid detection methods for steroid hormones in animal derived foods

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DOI 10.19812/j.cnki.jfsq11-5956/ts.20250109002
刊名
Journal of Food Safety and Quality
年,卷(期) 2025, 16(9)
作者
作者单位

华北理工大学化学工程学院;
宁波海关技术中心;
中国科学院宁波材料技术与工程研究所

摘要
动物源性食品是人类重要的营养素来源之一。在养殖过程中, 类固醇激素的合理使用可达到促生长、增重、消炎等目的, 但过渡滥用会严重威胁食品安全和消费者身体健康。目前, 类固醇激素的检测方法主要为液相色谱法、气相色谱法及其与质谱的联用技术, 这严重依赖大型精密仪器、预处理复杂, 并且需要专业实验室和技术人员。近些年来, 随着分析科学技术与仪器的飞速发展, 各种类固醇激素残留的快速检测技术已不断涌现, 为食品安全提供了坚实的技术保障。本文对目前类固醇激素的快速检测方法, 包括电化学法、比色法、荧光/磷光法、拉曼光谱法和侧流免疫层析法进行了详细综述, 分析了这些方法的优点及不足, 探讨了其面临的挑战及未来的发展方向。该综述将为食品中类固醇激素残留的快速检测方法的设计提供参考借鉴, 并对相关研究者提供思路启发。
Abstract
Animal derived foods are one of the important sources of nutrients for humans. During the breeding process, the rational use of steroid hormones can achieve the goals of promoting growth, weight gain and anti-inflammatory effects, but excessive abuse can lead to serious threats to food safety and consumer health. At present, the detection methods for steroid hormones mainly rely on liquid chromatography, gas chromatography and their combined techniques with mass spectrometry. They also heavily rely on large precision instruments and complex preprocessing, requiring professional laboratories and technical personnel. In recent years, with the rapid development of analytical science and technology, rapid detection technologies for various steroid hormone residues have emerged, providing solid technical support for food safety. This paper presented a comprehensive review of current rapid detection methods for steroid hormones, including electrochemistry, colorimetric methods, fluorescence/phosphorescence methods, Raman spectroscopy and lateral flow immunoassay. It analyzed the advantages and disadvantages of these methods, discussed the challenges they face, and explored their future development directions. This review served as a reference for the design of rapid detection methods for steroid hormone residues in food and provided insights and inspiration for relevant researchers.
关键词
类固醇激素;快速检测;电化学法;比色法;免疫层析法;表面增强拉曼光谱法;荧光检测法;研究进展
KeyWord
steroid hormones; rapid detection; electrochemistry; colorimetric assay; immunochromatography; surface enhanced Raman spectroscopy; fluorescence assay
基金项目
页码 159-171
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薛耀辉, 李锦花, 马 明, 钱四化, 韩 超*, 王宇辉*. 动物源性食品中类固醇激素的快速检测方法研究进展 [J]. 食品安全质量检测学报. 2025; 16; (9). 159 - 171.

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