观察并发肝功能损害的急性结石性胆囊炎手术治疗临床效果-国际外科研究杂志-CSCIED科技核心评价数据库-手机版

观察并发肝功能损害的急性结石性胆囊炎手术治疗临床效果

Observation on the clinical effect of surgical treatment of acute calculous cholecystitis complicated with liver function damage

ES评分 0 浏览量：972 下载量：0

全文阅读下载引用收藏

DOI	10.12208/j.ijsr.20220094
刊名	国际外科研究杂志 International Journal of Surgical Research
年，卷(期)	2022, 5(4)
作者	韩乌日吉勒*,
作者单位	内蒙古兴安盟人民医院内蒙古乌兰浩特 ;
摘要	探讨发生急性胆结石胆囊炎时存在肝功能损伤接受手术治疗的具体情况。方法选取200例2020年3月-2021年3月在本院接受治疗的急性结石性胆囊炎患者进行研究，均发生肝功能损伤，按照炎症程度将其分成三组，即轻度组（78例）、中度组（69例）、重度组（53例），分析三组的肝功能指标。结果三组患者中，重度组的IL-8、IL-6、CRP水平高于中度组，而中度组高于轻度组；相较于轻度组与中度组，重度组的AST、TBIL、ALT水平均较高，ALB水平较低，而中度组的AST、TBIL、ALT水平较轻度组高，ALB水平较轻度组低（P＜0.05）。结论以手术的方式治疗急性结石性胆囊炎并发肝功能损害能够获得较好的疗效，并且能够促进患者肝功能恢复。
Abstract	Objective: To investigate the specific situation of surgical treatment of liver function injury in patients with acute cholecystolithiasis and cholecystitis. Methods: 200 patients with acute calculous cholecystitis who were treated in our hospital from March 2020 to March 2021 were selected for study. All patients suffered from liver function injury. They were divided into three groups according to the degree of inflammation, namely, mild group (78 cases), moderate group (69 cases), and severe group (53 cases). The liver function indexes of the three groups were analyzed. Results: The levels of IL-8, IL-6 and CRP in severe group were higher than those in moderate group, while those in moderate group were higher than those in mild group; Compared with the mild group and the moderate group, the levels of AST, TBIL, ALT in the severe group were higher and the levels of ALB were lower, while the levels of AST, TBIL, ALT in the moderate group were higher and the levels of ALB in the mild group were lower (P<0.05). The total effective rate of the three groups was 95.50%. Conclusion: Surgical treatment of acute calculous cholecystitis complicated with liver function damage can achieve good results, and can promote the recovery of liver function.
关键词	急性胆结石胆囊炎；并发肝功能损害；手术；临床效果
KeyWord	Acute gallstone cholecystitis; Complicated with liver function damage; operation; Clinical effect
基金项目
页码	16-18

参考文献
相关文献

[1] 贾晓斌.急性胆囊炎合并肝功能异常手术时机的探讨
[J].中国现代医生,2020,58(15):56-58.

[2] Alam A S , Barker J , Lituri D . Concurrent Presentation Of Acute Cholecystitis And Acute Appendicitis In A Paediatric Patient
[J]. Internet Scientific Publications, 2019(1).

[3] 温永春.并发性肝功能损害的急性结石性胆囊炎手术治疗的临床效果体会
[J].中国现代药物应用,2016,10(20):19-20.

[4] 李斌.40例老年急性结石性胆囊炎手术治疗的临床效果观察
[J].世界最新医学信息文摘,2017,17(31):172.

[5] De Santibanes M, Glinka J, Pelegrini P, et al. Extended antibiotic therapy versus placebo after laparoscopic cholecystectomy for mild and moderate acute calculous cholecyst itis: A randomized double-blind clinical trial
[J]. Surgery, 2018, 164(1): 24-30.

[6] 杜丰杰.并发肝功能损害的急性结石性胆囊炎手术治疗的临床价值观察
[J].中国实用医药,2016,11(27):121-122.

[7] 俞鑫苗,陈伟鑫,张军苗.不同手术时机腹腔镜胆囊切除术治疗急性结石性胆囊炎的疗效及中转开腹影响因素研究
[J].浙江创伤外科,2018,23(03):480-482.

[8] Turco Luigi Carlo,Tortorella Lucia,Tuscano Attilio,Palumbo Marco Antonio,Fagotti Anna,Uccella Stefano,Fanfani Francesco,Ferrandina Gabriella,Nicolotti Nicola,Vargiu Virginia,Lodoli Claudio,Scaldaferri Franco,Scambia Giovanni,Cosentino Francesco. Surgery-related complications and long-term functional morbidity after segmental colo-rectal resection for deep infiltrating endometriosis (ENDO-RESECT morb).
[J]. Archives of gynecology and obstetrics,2020,302(4).

[9] 董永光,慕海峰.急性结石性胆囊炎腹腔镜胆囊切除术的可行性
[J].河南外科学杂志,2019,25(05):12-13.

[10] 李冬冬,江涛,周绍荣,焦兰农,姚建根.腹腔镜胆囊切除术治疗急性结石性胆囊炎的疗效及安全性分析
[J].肝胆胰外科杂志,2019,31(08):493-495.

[11] Ke C W, Wu S D. Comparison of Emergency Cholecystectomy with Delayed Cholecystectomy After Percutaneous Transhepatic Gallbladder Drainage in Patients with Moderate Acute Cholecystitis
[J]. J Laparoendosc Adv Surg Tech A, 2018, 28(6): 705-712.

[12] 王志晓.腹腔镜手术治疗急性结石性胆囊炎对炎性因子水平与胃肠功能的影响
[J].中外医学研究,2019,17(21):112-114.

[13] 叶刚.急性结石性胆囊炎患者采用腹腔镜手术治疗的疗效及安全性评价
[J].中国实用医药,2019,14(12):8-10.

[14] Wakabayashi G, Iwashita Y, Hibi T, et al. Tokyo Guidelines 2018 surgical management ofacute cholecystitis: safe steps in laparoscopic cholecystectomy for acute cholecystitis (with videos)
[J]. J Hepatobiliary Pancreat Sci, 2018, 25(1): 73-86.

[15] 王春云,李红梅.不同手术时机行腹腔镜下胆囊切除术治疗急性结石性胆囊炎的临床效果分析
[J].世界最新医学信息文摘,2019,19(A2):78-79.

[16] 李渊.腹腔镜手术治疗急性结石性胆囊炎对炎性因子水平及胃肠功能的影响
[J].黑龙江医学,2019,43(04):323-324.

[17] 于云宝.结石性胆囊炎患者开腹及腹腔镜手术切除胆囊治疗效果比较
[J].中西医结合心血管病电子杂志,2019,7(16):33.

[18] 叶建龙.并发性肝功能损害的急性结石性胆囊炎手术治疗的临床效果分析
[J].生命科学仪器,2022,20(S1):112+116.

[19] 刘小芳,陈先锋,蒋胜.急性结石性胆囊炎经腹腔镜胆囊切除术治疗时机对并发症的影响及中转开腹危险因素分析
[J].临床误诊误治,2020,33(07):62-66.

引用本文

韩乌日吉勒*. 观察并发肝功能损害的急性结石性胆囊炎手术治疗临床效果 [J]. 国际外科研究杂志. 2022; 5; (4). 16 - 18.

文献评论

相关学者

相关机构